Therefore, although there are different approaches one can use, a very helpful mnemonic that systematically includes most of the major categories is VINDICATE!!! To remember this mnemonic, keep in mind that after we've generated a differential diagnosis and used the techniques of refining probability, we will feel VINDICATEd!!! by obtaining the most likely diagnosis! This mnemonic combines anatomic, pathophysiologic, and systems approaches and can be applied successfully.
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